ORTHO TRI-CYCLEN LO
Tolerability
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Tolerability


Choose ORTHO TRI-CYCLEN LO for the tolerability she wants. With a low discontinuation rate, ORTHO TRI-CYCLEN LO has an excellent tolerability profile.


Headache

Emotional Liability

Nausea

Cervical Dysplasia

Abdominal Pain

Acne

Migraine

Weight Increase
0.6%

0.5%

0.4%

0.5%

0.3%

0.2%

0.4%

0.1%

0.4%

0.3%

0.4%

0.3%

0.2%

0.2%

0.1%

0.5%


A randomized, multicenter study comparing ORTHO TRI-CYCLEN LO regimen with a 20-mcg comparator regimen; two thirds of participants received study drug for 6 cycles and one third for 13 cycles. There were no statistically significant differences in any adverse events leading to the discontinuation of ORTHO TRI-CYCLEN LO vs a 20-mcg comparator.

Low Discontinuation Rate

In a clinical trial of over 2,000 women, ORTHO TRI-CYCLEN LO had a low discontinuation rate (4%) due to adverse events. The most frequent adverse events resulting in discontinuation were headache, cervical dysplasia, emotional liability, nausea and abdominal pain.

Adverse Events

The most common treatment-emergent adverse events for ORTHO TRI-CYCLEN LO were headache (29.4%); upper respiratory tract infection (16.8%); nausea (14.7%); abdominal pain (13.7%); breast pain (9.8%); dysmenorrhea (9.7%); and sinusitis (9.1%).
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